Die is a dark fantasy tale, described by the writer as "goth Jumanji". That should be enough to get you to check out the first issue, and I am certain you'll want to keep reading afterwards. I'd also mention Stephen King's It and the old D&D cartoon as influences. The toon is mentioned as a major inspiration in the back of the issue, actually.
Gillen established the tone quickly, and the writing was superb throughout. Mix in excellent art from Stephanie Hans, and you have a winner.
The bar is set high in this debut. I just hope the rest of volume one keeps it up.